<i>CTLA-4</i> Gene Polymorphism in Women with Idiopathic Recurrent Pregnancy Loss
نویسندگان
چکیده
منابع مشابه
Association Of rs16260 Polymorphism Of CDH1 Gene With Recurrent Pregnancy Loss In Iranian-Azeri Women
Background & aim: Recurrent pregnancy loss is defined as loosing at least 2 pregnancies before 20th weeks of gestation. Besides all the known causative factors, in about half of the cases, the causing factor, remains unknown. In recent years, some studies have shown the role of candidate genes polymorphisms in RPL. CDH1 is one of these candidate genes that plays critical role in embryo implanta...
متن کاملGlobal alteration in gene expression profiles of deciduas from women with idiopathic recurrent pregnancy loss.
Recurrent pregnancy loss (RPL) occurs in ∼5% of women. However, the etiology is still poorly understood. Defects in decidualization of the endometrium during early pregnancy contribute to several pregnancy complications, such as pre-eclampsia and intrauterine growth restriction (IUGR), and are believed to be important in the pathogenesis of idiopathic RPL. We performed microarray analysis to id...
متن کاملAssociation between Thrombophilic Gene Polymor-phisms and Recurrent Pregnancy Loss in Iranian Women
Background: Recurrent pregnancy loss (RPL) is a common problem among couples, and acquired thrombophilia is the well-known etiology of RPL. The aim of this study was to establish the association between inherited thrombophilic gene polymorphisms and RPL. Methods: This case-control study was conducted on 50 women with unexplained RPL and 50 parous women with no history of miscarriage (age range...
متن کاملAnalysis of Missense Mutations of CX3CR1 Gene in Patients with Recurrent Pregnancy Loss Using Bioinformatics Tools
Introduction: Abortion is a common complication that refers to the early termination of pregnancy with the death of the fetus before the 20th week of pregnancy. Previous studies show that many genes are involved in this disease, including the CX3CR1 gene, which is one of the inflammatory response genes in the immune system. The pathogenicity of these variants was determined in this study using ...
متن کاملmethylenetetrahydrofolate reductase c677t and a1298c polymorphism in iranian women with idiopathic recurrent pregnancy losses
background recurrent pregnancy loss (rpl) is a serious problem for pregnancy. there is evidence that vascular complications play a principal role in rpl. methylenetetrahydrofolate reductase (mthfr) is a key enzyme in folate metabolism. polymorphisms (c677t, a1298c) of mthfr gene are associated with decreased mthfr activity. objectives the aim of this study was to determine the association betwe...
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ژورنال
عنوان ژورنال: International Journal of Genetics and Genomics
سال: 2016
ISSN: 2376-7340
DOI: 10.11648/j.ijgg.20160404.11